University of Hawai’i
John A. Burns School of Medicine
Department of Cell and
Molecular Biology
Model: Presynaptic-like Varicosity
Showing relationship between nicotinic acetylcholine receptors (nAChR) and voltage gated calcium channels (VGCC).
Research in our laboratory is focused on the regulation of the presynaptic nerve terminal:
❖ Beta amyloid (Aβ) regulation of presynaptic calcium
❖ Lipid rafts in Aβ regulation
❖ Nicotine regulation via presynaptic nicotinic receptors
❖ Calcium homeostasis
Last updated June 17, 2010
Copyright © 2010 Robert Nichols, M.D., Ph.D. All rights reserved.
Site design Michelle Jhun
Model: α7 Nicotinic Receptor
Shown with associated Lipid Raft on one side and Aβ oligomer (in grey circles).