The Science of Sleep

PHYL 160

Instructor: John D. Rand, Ph.D.                Office:  Kokio 209B

Phone:  734-9433                                        Office Hours:  TTh: 10:30 – 11:00

Course No:  PHYL 160                               Lecture Time:  TTh 9:15 – 10:30

Lecture Room:  KOKIO 202C                               Credits:  3 hrs.

Course Website: http://www2.hawaii.edu/~jrand/Physiology/PHYL160/index.htm

Textbook: Understanding Sleep and Dreaming by William H. Moorcroft,    Kluwer/Plenum Publishing, 1^st Edition, New York, NY 2003.

Basics of Sleep Behavior by the Sleep Research Society, (On-line Textbook), UCLA School of Medicine and SRS, Los Angeles, CA 1993.

(website:http://www.sleephomepages.org/sleepsyllabus/)

Course Description:  An introduction to the science of sleep, sleep research and medical disorders associated with sleep.  This course will include an overview of the anatomy and physiology of the central nervous system as it is related to sleep.  The student will learn how to recognize healthy sleep and will be introduced to the methods sleep researchers use to diagnose both healthy and disordered sleep.

Course Goals:  Upon completion of this course, the student should be able to:

§ demonstrate knowledge of how sleep is regarded in different cultures and environments. 

§ demonstrate knowledge of the history of sleep research.

§ demonstrate an understanding of how sleep changes from infancy to the elderly.

§ demonstrate an understanding of polysomnography and other methods of analysis of sleep quality.

§ demonstrate knowledge of the anatomy and physiology of sleep centers in the central nervous system.

§ demonstrate knowledge of the neuroendocines and their effects on sleep.

§ demonstrate an understanding of sleep stages, patterns and other features associated with sleep and sleep disorders.

§ utilize and interpret physiological signals to evaluate sleep quality and sleep disorders.

§ demonstrate an understanding of how researchers evaluate sleep quality and sleep disorders.

§ demonstrate an understanding of current theory of why we sleep and possible causes of sleep disorders.

Course Information and Website: This course meets twice a week for one semester.  Class time will involve lectures and group discussions.  Attendance and student participation is required during all scheduled class times.

Method of Evaluation:

Research Project (Sleep Journal & Poster)           100 points     

Exam 1                                                                       100 points

Exam 2                                                                       100 points

Final Exam (Dec. 16, 2004) 7:45 – 9:45a 200 points

Total Points                                                             500 points

                        A         500-450 points

                        B         449-400 points

                        C         399-350 points

                        D         349-300 points

                        F          below 300 points

Exam scores may be evaluated on a curve at the instructor’s discretion.  A missed exam will result in an ‘F’ grade.  Students who participate as a research subject in KCC’s HRV study will receive 20 points of extra credit toward their final grade.  See your instructor for details. 

Students with disabilities:

Extended time in a distraction-free environment is an appropriate accommodation based on the student’s disability.  If you do have a disability and have not voluntarily disclosed the nature of your disability and support you need, you are invited to contact the Special Student Services Office, 734-9552, Ilima 105.

Withdrawal and Incomplete Policy:

Students who disappear from the course with no withdrawal form processed will earn an ‘F” grade.  Course withdrawal dates are published in the KCC Sp. 2004 schedule of classes.  Incomplete grades (‘I’) are only granted in extreme cases involving an emergency or an unavoidable circumstance.

Important Notices:

· Class is cancelled if, without prior notice, the instructor is 20 minutes late.

· If you cannot attend the lecture you should obtain lecture notes from a fellow student

· Please turn off cell phones and pagers during the lecture, and especially during exams.

· Students are advised to organize, summarize, and rewrite notes for review.  The data standard for the course is the textbook, with heavy reliance on lecture notes.

· Students can check with the instructor at any time for your current class standing.

Tenative Lecture Schedule:  The tentative lecture/discussion schedule is as follows:

(BSB – Basics of Sleep Behavior, USD – Understanding Sleep and Dreaming)

LECTURES TOPICS READING

            WHAT IS SLEEP? (2)                                                                BSB A. p. 1-12

                                    Defining Sleep                                                   POSUSD p. 1-17          

                                    Sleep deprivation studies (factors)

Global attitudes toward sleep

            SLEEP DEBT (2)                                                                       BSB D. p. 69-71

                                    Light pollution and modern society                       POSUSD p. 18-35

                                    Multiple sleep latency test (MSLT)

                                    Relationship to circadian rhythms

            SLEEP RESEARCH (2)                                                                                                                                      Sleep labs - sleep recording                                POSUSD p. 36-57

                                    Polysomnography, EEG

                                    Sleep stages and signal patterns

            GOOD SLEEP HYGIENE (2)                                                      BSB C. p. 45-56

                                    Sleep maturation (infancy-geriatrics)                    USD p. 58-78POS                                                          The role of light an other stimuli

                                    Circadian rhythms (melatonin)    

            BRAIN AND PHYLOGENY OF SLEEP (4)                                   BSB B,E,F p.13-20, 33-44

                                    Human Brain Anatomy                                       POSUSD p. 79-97

                                    Human Brain Physiology

SLEEP PHYSIOLOGY (6)                                                          BSB G, J p. 21-32, 65-68

                                    Anatomy and Physiology of the CNS                   POSUSD p.97-120

                                    Sleep centers in the brain – hormones

            DREAMING (2)                                                                          BSB H. p. 57-60                                                Dream research                                                 POSUSD p. 121-204

                                    Current dream theories

            SLEEP DISORDERS     (3)                                                        BSB K, L. p. 69-78,

                                    Sleep Apnea (obstructive vs. central)                   USD p. 205-266

                                    Narcolepsy

                                    Insomnia

            SLEEP FUNCTION (2)                                                                BSB I. p 61-65.

POSUSD p. 267-315

                                    Sleep optimization

                                    Longevity and vitality

                                    Immune system defense network