FALL 1997
INSTRUCTOR: Dr. John M. Berestecky
OFFICE: KOKIO 105
Phone: 734-9123
E-mail: johnb@hawaii.edu
TEXT:
Microbiology: An Introduction; sixth edition. Tortora, Funke and Case. The Benjamin/Cummings Publishing Co., Inc. 1997. (T)
OPTIONAL TEXTS:
1.) Beginnings of Life. An Introduction to Cell, Molecular, and Developmental Biology. Second Edition; Ricki Lewis; Wm. C. Brown Publishers. 1995 (L)
2.) Study Guide for Microbiology: An Introduction; Berdall R. Funke; The Benjamin/Cummings Publishing Co., Inc. 1995.
ADDITIONAL READINGS:
1.) Microbiology Readings. Microbiology 130. (MR). On reserve in the KCC Library.
2.) Microbiology Study Guides. Volumes I, II, III. On reserve in the KCC Library.
WORLD WIDE WEB:
As you can see, a world Wide Web page has been developed for this course. A number of important resources, including study guides and lecture outlines can be found at this address:
http://www2.hawaii.edu/~johnb/micro
MICROBIOLOGY LIST:
All students are REQUIRED to have an e-mail account. You can get a free one at the computing center. All students are REQUIRED to join the KCC Microbiology e-mail list through which all manner of discussion will take place. You can subscribe to the list by sending a message to:
In the message you say:
SUBSCRIBE KCCMICRO-L yourfirstname yourlastname
MEETING TIMES:
6745 T, Th: 12:00-1:15 PM Olapa 106
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8/26 |
Introduction and History |
Chapter 1 (T); Chap 1 and 2 especially pg. 10, 16-29(L); "A Biologist Whose Heresy Redraws the Earth's Tree of Life" (MR) |
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8/28 |
Basic properties of cells |
Chapter 4 (T); Chap 4(L); "How a Mysterious Disease Laid Low Europe's Masses" (MR); "Profiles in Chinatown Courage" (MR); "Interview: David Stannard" (MR)
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9/2 |
Basic properties of cells |
Chapter 4 (T); Chap 5(L) |
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9/4 |
Procaryotic cells (Skin and Eye Infections) |
(Chapter 21 (T)) |
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9/9 |
Procaryotic cells |
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9/11 |
Eucaryotic cells (Nervous System Infect.) |
"The Perils of Treading on Heredity" (MR) (Chapter 22(T)) |
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9/16 |
Basic chemistry |
Chapter 2 (T); Chap 3 (L) |
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9/18 |
Microbial metabolism |
Chapter 5 (T); Appendix C (T); Chap 6 (L) |
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9/23 |
Microbial metabolism (Cardiovascular System infections) |
Chapter 5 (T); Chap 7 (L) (Chapter 23 (T)) |
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9/25 |
Microbial metabolism |
Chapter 5 (T); Outline Due-Chap. 21,22,23 |
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9/30 |
Microbial genetics |
Chapter 8(T); pg. 268 (L), Look at the pictures in Chapters 13 and 14 (L). Read Chapter 15 (L).; "The Cruel Logic of Our Genes" (MR); "James Watson and the Search for Biology's 'Holy Grail'"(MR)
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10/2 |
FIRST MIDTERM EXAM |
covers thru metabolism |
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10/7 |
Microbial Genetics (Respiratory system infections) |
Chapter 8 (T); Chapter 15 (L) (Chapter 24 (T)) |
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10/9 |
Microbial genetics |
Chapter 8 (T); Chap 16 (L) |
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10/14 |
Microbial genetics Recombinant DNA and Biotech (Digestive system infect.) |
Chapter 9 (T); Chap 17 (L) (Chapter 25 (T)) |
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10/16 |
Microbial growth |
Chapter 6 (T) |
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10/21 |
Control of microbes |
Chapter 7 (T) |
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10/23 |
Antimicrobial drugs (Urinary and reproductive system infections) |
Chapter 20 (T) (Chapter 26 (T)) |
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10/28 |
Viruses Cancer Fungi and protozoa Outline Due-chap 24,25,26 |
Chapter 13 (T); Chap 4, pg 79 - 81(L); Chap 9, pg 179-187(L); "Taming the Wily Rhinovirus" (MR) Chapter 12 (T) |
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10/30 |
Viruses and Cancer |
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11/4 |
SECOND MIDTERM EXAM |
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11/6 |
Infectious disease epidemiology |
Chapter 14 (T) |
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11/11 |
Holiday - Veteran's Day |
Chapter 15 (T) Chapter 16 (T) |
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11/13 |
Pathogenic mechanisms of parasites Host-parasite relationships |
Chapters 15 (T) Chapter 16 (T) |
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11/18 |
Immune system Antibodies |
Chapter 17 (T) Chapter 18 (T) |
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11/20 |
Cellular immune mechanisms |
Chapter 17 (T) Chapter 18 (T) |
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11/25 |
Immunopathology Allergy and autoimmunity Immunodeficiency and AIDS |
Chapter 19 (T) "Bloodstream Follies" (MR); "My Life Stalking AIDS" (MR); "The Human Mouse" (MR); "Uganda: Land Beyond Sorrow" (MR). |
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11/27 |
Holiday - Thanksgiving |
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12/2 |
THIRD MIDTERM EXAM - OPEN BOOK COVERS CHAPTERS 21 - 26 TORTORA ET.AL. |
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12/4 |
Sexually transmitted disease Skin and eye infections |
Chapter 26 (T) Chapter 21 (T); "Tiny Tick, Big Worry" (MR) |
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12/9 |
Nervous system infections Respiratory infections |
Chapter 22 (T) ; pg 68 -69 (L) Chapter 23 (T); "Septic Shock" (MR); "Tuberculosis Today" (MR) |
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12/11 |
Blood and Systemic infections Food and waterborne infections |
Chapter 24 (T) Chapter 25(T) |
EXAMINATIONS:
Three midterm exams and a final exam are scheduled for a total of 250 points. Each midterm will be worth 50 points (20% of the total course points). The final exam will be worth 100 points (40% of the total course points). These exams will be machine graded and all students must bring a No. 2 pencil to the exams for marking the test forms.
Exams will cover the assigned reading as well as the lecture content.
Only one (1) make-up exam will be given on the last scheduled day of class (12/11/97). The make-up exam will cover the first 2/3's of the semester and any student who misses either the first or the second midterm for good cause may take it. Anyone who misses two or more midterms should withdraw from the course as there is no way to make up two or more exams. If you miss the final exam for good cause you must make arrangements with the instructor to take the make-up exam.
FINAL EXAM: Thursday, Dec. 18 at 12:15 - 2:15 PM
GRADING:
Your final letter grade will be determined by your standing on a class curve of all final scores. In order to score a "C" in this course you must have accumulated 150 points (60% of 250 possible points). An "A" grade respresents excellence in understanding and performance and generally the top 10% of the class earn an "A". The next 15% of the class usually scores a "B" grade which represents good, above average understanding and performance.
OBJECTIVES:
1. The student shall study and learn the basic vocabulary of microbiology
2. The student shall study and learn how life is organized at the cellular and subcellular levels
3. The student shall study and learn the fundamental biochemistry of cellular metabolism
4. The student shall study and learn the basic principles of molecular genetics as they relate to cell division, mutation, genetic engineering, and antibiotic resistance
5. The student shall study and learn the principles of sterilization, disinfection and aseptic technique as well as the principles of antibiotic therapy
6. The student shall study and learn the principles of the host parasite relationship both in health and in disease
7. The student shall study and learn the components of the human immune system and how they interact in generating an immune response
8. The student shall study the major and the common infectious diseases of humans
9. The student shall become literate in basic microbiology
The Math / Science Department policy on WITHDRAWAL and INCOMPLETE grades is as follows:
1. WITHDRAWALS - After the last day for withdrawals (Oct. 24, 1997), the instructor will sign withdrawals only in cases of extreme or unusual circumstances. Grade related excuses are NOT acceptable reasons for withdrawing from the course after the deadline.
2. INCOMPLETES - Students must present the "Request for Incomplete" form to the instructor prior to the last day of instruction. An "I" grade will only be given to students who are achieving passing grades and who are very close to completing the course. In addition, such students must have a very good reason for not being able to complete all the course work on time. Incomplete grades must be made-up by the deadline in the following semester; if they are not made-up by the deadline they normally revert to an "F".
SERVICE LEARNING OPTION:
You may receive credit for performing a community service project which reinforces and applies some of the principles of microbiology you are learning in this course. This Service Learning Project is worth 50 points and the grade you earn in the project will replace your lowest midterm exam score.
Suitable Service Learning projects can be chosen by first discussing your interests and ideas with me and by reviewing the Service Learning Community Agency Handbook for placement opportunities. HIV/AIDS prevention and education as well support for people infected with HIV and opportunistic pathogens are obvious areas of service for students in this class and there are a number of opportunities available with agencies that work in these areas. There are also teaching and tutoring opportunities for high school and intermediate school students about infectious disease and HIV as well as other aspects of microbiology. This type of teaching experience would be especially important for those of you who plan to be teachers since 40 hours of field experience is required for admission to the UH College of Education. Service Learning projects may also be found at the Waikiki Aquarium and at Lyon Arboretum.
A successful project will involve at least 20 hours of service. You are required to keep a ongoing journal in which you describe and analyze your service learning experience. In this journal you should attempt to connect the service learning experience to your microbiology class. All projects must begin by Sept. 26, 1997.
EXTRA CREDIT:
You may choose to write up to TWO critical review papers, 2-3 typed pages long (10 or 12 point font, double spaced) for a total of 10 extra points (5 points per paper). These papers are to be critical reviews of the biology (preferably microbiology, immunology or infectious disease) articles featured in SCIENTIFIC AMERICAN. (These SCIENTIFIC AMERICAN articles are the long feature articles not the short news review articles. The feature articles all conclude with a bibiliography list for reference or further reading.)
In your review of the article, please describe the central theme and any controversies or problems that are discussed or developed int the article. Describe the concepts in the article which are important and say why you thought them to be important. Research something in the article which you had a hard time understanding and then restate it based on your research.